I'm reading Bloom on The Winter's Tale and Leontes nihilism is discussed. Bloom sees Iago and Iachimo and Edmond all nihilists to various degrees. When you believe in nothing, anything is possible, there are no limits.
That got me thinking about one of my favorite movies, The Big Lebowski. There are actual nihilists in the move. Nobody really espouses nihilism. I think even in the hope of anarchy and libertarianism, that underneath the humanity of people will self regulate.
Nihilism is to be avoided in Buddhism, it is seen as the polar opposite of eternalism.
Stephen Batchelor is seen as a materialist by some Buddhists. Of course nobody is a materialist, because you can't 5 sense the theory. There seems to be some push pull between modern skeptical people and the mythology of Buddhism.
I think the other default negative mind virus is materialism, the idea that material things make you happy. I think a lot of viruses take hold in the vacuum of nihilism: hedonism, egotism. The best way to be is altruistic.